For treatment of transplant (kidney, liver, and heart) rejection, rheumatoid arthritis, severe psoriasis.
How it works
Cyclosporine binds to cyclophilin. The complex then inhibits calcineurin which is normally responsible for activating transcription of interleukin 2. Cyclosporine also inhibits lymphokine production and interleukin release.
Common side effects
Hypertension, gingival hypertrophy, hypertrichosis, paraesthesia, hepatoxicity, tremor, hyperkalaemia., acne, facial oedema
What is Cyclosporine?
Cyclosporine is an immunosuppressive drug meaning it suppresses your body’s immune power. The immune system helps your body to guard against invading foreign bodies which can cause infections and illnesses thereby preventing common or dangerous diseases. The same immune system can be a disadvantage during an organ transplant as it will treat the organ to be implanted as a foreign body and your body will reject it (organ) completely from integrating.
Cyclosporine is used along with other medications to stop your body from rejecting a transplanted heart, liver, or kidney. This medication may also be given for conditions other than that mentioned here. Cyclosporine oral is sold under various trade names, a couple of which are Sandimmune and Panimum (made by Panacea (India)).
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